Solutions · 340B Performance

340B has never been more complex - or more scrutinized. We make it manageable, and provable.

Data demands, manufacturer restrictions, audits, and a rebate model that is no longer hypothetical. EngineRx pairs claim-level software with operators who have run 340B from the inside - so you capture everything you're entitled to, and can prove it.

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OPTIMIZATION ENGAGEMENTS

10-20% average savings uplift

TOTAL RECOVERED

$500M total recovery across engagements

FOOTPRINT

300+ facilities supported on 340B

The software

The Vitalyze EngineRx intelligence layer automates the entire pharmacy enterprise.

Four integrated intelligence modules creating automated processes:

01 - THE FOUNDATION

Drug Data Intelligence

Every purchase, claim, and administration record normalized to one claim-level truth. The map above starts here.

In the platform →
02 - THE WATCHDOG

340B Intelligence

Split-billing integrity, eligibility and scope mapping, contract pharmacy and TPA oversight - the ✓ beside every node above.

In the platform →
03 - THE LENS

Mixed Drug Use

Mixed-use analyzed at the NDC level across inpatient and outpatient - WAC reduction found, accumulators validated, and 340B spend maximized.

In the platform →
04 - THE COLLECTOR

Savings Optimization

Every dollar of spend watched to maximize 340B purchasing - expected versus received, flagged rows disputed, recoveries tied to cash.

In the platform →

Maintaining your 340B pricing

The data that keeps your 340B pricing.

Manufacturers increasingly condition 340B pricing on the timely submission of claims-level utilization data. Miss a submission window or send malformed data, and statutory pricing can lapse across your covered entities. EngineRx structures each submission to the manufacturer’s specification, delivers it on schedule, and keeps the audit trail - so your 340B pricing never depends on a spreadsheet.

01

Submission-grade claims data

Structured, on-time delivery to each manufacturer's specification - formats maintained as specs change.

02

Eligibility documented on every claim

Claim-level audit trails that survive manufacturer review - nothing paid back for lack of proof.

03

Deadlines tracked, shortfalls disputed

Expected 340B value reconciled against what actually arrives - and pursued when it doesn't.

04

Ready for the HRSA rebate pilot

The HRSA rebate-model pilot will re-emerge. When it does, the same submission infrastructure - built, tested, and already running - is the head start.

The advisory services

From Raw Data to Actionable Intelligence

Software finds it; specialists who have run 340B from the inside get it done.

Hospital split-billing audits and 340B pricing audits

Retail and contract pharmacy network analysis

340B site modeling, scope buildout, and implementation project management

Specialty pharmacy feasibility and buildout

Documented impact

$136M identified at one system. 50+ health systems served.

Every number ties back to specific dispenses, NDCs, and claims. These engagements are anonymized; the figures are exact.

Large academic health system

Fragmented data, unified into a documented $136M opportunity.

Across 900+ physician and hospital departments, Vitalyze unified pharmacy data into a documented $136M opportunity - $34M available immediately from 340B expansion and $8.2M modeled from PBM displacement. Every figure ties to specific dispenses, NDCs, and claims.

4.2M PRESCRIPTIONS ANALYZED · 900+ DEPARTMENTS RECONCILED

$136M

Total opportunity identified

$34M

Immediate 340B expansion savings

−$8.2M

PBM spend displaced - removed from the cost base

$25.8M

Net immediate savings impact

“They helped us uncover millions in unclaimed 340B savings while ensuring full compliance.”
- CHIEF PHARMACY OFFICER, MIDWEST HEALTH SYSTEM

Keep exploring

The EngineRx platform → Pharmacy Network Optimization → Rebate Recovery → MFP Reconciliation →

Start with a 340B opportunity assessment.

A structured review of qualification rates, missed capture, and compliance exposure - scoped in one call.

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